The U.S. Food and Drug Administration has approved Saxenda (liraglutide) for chronic weight control in obese patients aged 12 and older. Saxenda has been approved for chronic weight control in adults with a BMI of 30 kg/m2 or more, or in adults with a BMI of 27 kg/m2 or more who have at least…
Researchers from the Rutgers Medical School, New Jersey have reported that vitamin D regulates calcium in a section of the gut that was previously thought not to play a key role. The findings have important implications on how gut disease, including ulcerative colitis and Crohn’s disease, can alter calcium regulation. The study This…
Researchers have found that a treatment with icodec insulin once a week successfully reduced blood sugar and had a safety profile similar to that of glargine U100 insulin administered once a day in patients with type 2 diabetes, according to a study published in the New England Journal of Medicine. It is often thought…
A common weight loss surgery for obese teenagers called sleeve gastrectomy has damaging effects on bones, according to a new study. “Childhood obesity is a major public health problem that has increased over the past 10 years,” lead researcher Miriam A. Bredella, MD, said. She is professor of radiology at Harvard Medical School in…
Gut hormones Gut hormones play an important role in the regulation of fat production in the body. A key hormone released a few hours after eating shuts down fat production by regulating gene expression in the liver. Nevertheless, this regulation is abnormal in obesity, researchers from the University of Illinois Urbana-Champaign found in a…
Obese patients older than 60 years of age can lose as much weight as younger people only through lifestyle changes, according to a new study by the University of Warwick NHS Trust and the University Hospitals of Coventry and Warwickshire (UHCW). The study shows that age is not a hurdle to lose weight. The…
Obesity is a global epidemic that causes millions of deaths each year; it is a chronic disease associated with other serious and chronic conditions, which include type 2 diabetes, coronary artery disease, stroke, cancer, and depression, among others. In a new study, researchers have discovered that the hormone Lipocalin-2 can reduce hunger, leading to weight…
The incidence of nonalcoholic fatty liver disease (NAFLD) is increasing among children, but not all obese youngsters undergo recommended detection tests, a California study suggests. The study A group of researchers inspected Kaiser Permanent Southern California electronic medical record data from members ages 5 to 18 between 2009 and 2018, with records from…
A personalized obesity treatment plan based on phenotypes resulted in greater weight loss than that of standard care, according to a speaker from ObesityWeek Interactive. “We have classified obesity based on pathophysiology and behavioral phenotypes on abnormal satiation (hungry brain), abnormal postprandial satiation (hungry gut), emotional hunger (hedonic eating) and abnormal energy expenditure at…
Risk factors in early life – during the first 1000 days – aggregately predict increased obesity and cardiometabolic risk in early adolescence, according to new research conducted by the Harvard Pilgrim Health Care Institute. The study is the first to evaluate the combined influence of risk factors in early life with direct measures of adiposity…
Obesity is a serious global health problem and a risk factor for diseases such as type 2 diabetes, heart disease, and fatty liver disease. A crucial element in the development of obesity is adipose tissue, which encompasses fat cells (commonly called adipocytes, cells specialized in storing fat) and macrophages (purifying cells of the…
The prevention of heart attack and stroke in patients with type 2 diabetes treated at primary care should become a major priority. That is the conclusion of a study published on World Diabetes Day in the European Journal of Preventive Cardiology, a European Society of Cardiology (SEC) journal. The study “The most surprising…