Yogurt: The Nutrition Source Yogurt is a staple food in several cultures, originating from countries in Western Asia and the Middle East. The word yogurt is believed to be derived from the Turkish word “yoğurmak,” which means to thicken, coagulate, or curdle. Historical accounts describe nomadic herdsmen carrying milk in pouches made of animal…
A virus-like particle-based bivalent PCSK9 vaccine lowers LDL-cholesterol levels in non-human primates Abstract Elevated low-density lipoprotein cholesterol (LDL-C) is an important risk factor in the development of atherosclerotic cardiovascular disease (ASCVD). Inhibitors of proprotein convertase subtilisin/kexin type 9 (PCSK9), a negative regulator of LDL-C metabolism, have emerged as promising approaches for reducing elevated…
Abstract Gut microbiota is a microecosystem composed of various microorganisms. It plays an important role in human metabolism, and its metabolites affect different tissues and organs. Intestinal flora maintains the intestinal mucosal barrier and interacts with the immune system. The liver is closely linked to the intestine by the gut-liver axis. As the first…
There’s an air of cautious optimism about 2024, after a difficult few years following the end of the pandemic when investment in pharma and biotech research dropped substantially. After this significant reset, there’s now hope that in 2024, in line with emerging trends, the funds will be there for the vital clinical research and cutting-edge…
A Systematic Review and Meta-Analysis Question What is the association between 100% fruit juice intake and body weight in children and adults? Findings This systematic review and meta-analysis of 42 eligible studies, including 17 among children (n = 45 851) and 25 among adults (n = 268 095), found a positive association between intake…
The role of leptin and ghrelin in the regulation of food intake and body weight in humans: a review Summary Leptin and ghrelin are two hormones that have been recognized to have a major influence on energy balance. Leptin is a mediator of long-term regulation of energy balance, suppressing food intake and thereby inducing…
Small fish and bivalves offer often-overlooked nutritional and environmental value. Many health-conscious consumers have already cut back on hamburgers, steaks, and deli meats, often by swapping in poultry or seafood. Those protein sources are better than beef, and not just because they’re linked to a lower risk of heart disease, diabetes, and cancer.…
From gene therapy to Alzheimer’s treatment, predicting pancreatic cancer to pioneering reproduction methods, there were many promising discoveries in 2023 that will influence health and medicine COVID-19 has continued to claim lives in 2023, killing more than 50 thousand patients in the United States alone and bringing the global death toll to almost seven million people.…
Oral Health “There is no health without oral health.” You may have heard this statement but what does it mean? The health of our mouth, or oral health, is more important than many of us may realize. It is a key indicator of overall health, which is essential to our well-being and quality of life.…
Significant variations in the gut microbiome can be identified between people who develop pre-cancerous colonic lesions and those who do not. The Dutch study, abstract OP118, presented at United European Gastroenterology (UEG) Week 2023, held in Copenhagen, October 14–17, showed that the diversity of the gut microbiome was decreased in patients who went on…
Many gut microorganisms critical to human health rely on nutrients produced by each other for survival; however, these cross-feeding interactions are still challenging to quantify and remain poorly characterized. Abstract Here, we introduce a Metabolite Exchange Score (MES) to quantify those interactions. Using metabolic models of prokaryotic metagenome-assembled genomes from over 1600 individuals, MES…
The decision by an advisory committee may lead to Food and Drug Administration approval of the first treatment for humans that uses the CRISPR gene-editing system. A panel of experts said on Tuesday that a groundbreaking treatment for sickle cell disease was safe enough for clinical use, setting the stage for likely federal…