Colorectal cancer (CRC) is the second leading cause of cancer death in the United States. There is compelling evidence that screening to detect CRC early to find and remove precancerous polyps can reduce CRC mortality. However, screening has associated harms, including procedural complications, and inherent limitations. For example, colonoscopy, the most common screening tool in…
World obesity day 2023: Theme for this year is ‘Changing Perspectives: Let’s Talk About Obesity,’ according to the World Obesity Federation (World Obesity), a global organisation devoted solely to obesity. World Obesity Day is celebrated to promote practical solutions to assist people in achieving and maintaining a healthy weight, receiving proper treatment, and reversing the obesity…
Levels of health-promoting gut bacteria are linked with severity of fatigue symptoms, a study finds. Millions of people are affected by the debilitating exhaustion and brain fog that characterizes the long-term condition chronic fatigue syndrome (CFS), also known as myalgic encephalomyelitis. Although CFS has been connected to viral infections including COVID-19, the underlying cause of the…
The microbes in your gut can influence mental health, heart risk, weight gain and even sleep, which is why you need to eat a wider variety of quality food Every time you eat, you are feeding trillions of bacteria, viruses and fungi that live inside your gut. But are you feeding them the…
Is early-onset cancer an emerging global epidemic? Current evidence and future implications Abstract Over the past several decades, the incidence of early-onset cancers, often defined as cancers diagnosed in adults <50 years of age, in the breast, colorectum, endometrium, oesophagus, extrahepatic bile duct, gallbladder, head and neck, kidney, liver, bone marrow, pancreas,…
Ultra-processed food consumption, cancer risk and cancer mortality: a large-scale prospective analysis within the UK Biobank Background Global dietary patterns are increasingly dominated by relatively cheap, highly palatable, and ready-to-eat ultra-processed foods (UPFs). However, prospective evidence is limited on cancer development and mortality in relation to UPF consumption. This study examines associations between UPF…
Results of phase 3 trials testing gantenerumab are latest blow to amyloid hypothesis The second (and third) time was not the charm for Roche’s experimental antibody drug for Alzheimer’s disease. The company last night announced gantenerumab had failed to show a statistically significant benefit in two large, late-stage clinical trials that tested its ability to…
Fish is among the foods exerting favourable effects on colorectal cancer (CRC), but the possible role of canned fish has been insufficiently investigated. The research We aimed to investigate the relationship between canned fish consumption and CRC risk. We analysed data from two case–control studies conducted between 1992 and 2010 in several Italian…
Tocotrienols Attenuate White Adipose Tissue Accumulation and Improve Serum Cholesterol Concentration in High-Fat Diet-Treated Mice Tocotrienols (T3s), which are vitamin E homologs, have not only antioxidant function but also inhibitory effects on body weight gain and hepatic lipid droplet accumulation. However, the mechanisms of the anti-obesity effects of T3s are not yet understood. In…
The Best and Worst Foods for Acid Reflux A hot burning in the chest, a bitter taste in the throat, a gassy bloating in the stomach – acid reflux is no picnic. What you eat, however, can have an impact. The best and worst foods for acid reflux could spell the difference between sweet…
A Very Rare Variant in SREBF2, a Possible Cause of Hypercholesterolemia and Increased Glycemic Levels Abstract: Patients with high cholesterol and glucose levels are at high risk for cardiovascular disease.The Sterol Regulatory Element Binding Protein (SREBP) system regulates genes involved in lipid,cholesterol and glucose pathways. Autosomal Dominant Hypercholesterolemias (ADHs) are a groupof diseases…
Setting your clock: associations between timing of objective physical activity and cardiovascular disease risk in the general population Abstract Aims Little is known about the impact of daily physical activity timing (here referred to as ‘chronoactivity’) on cardiovascular disease (CVD) risk. We aimed to examined the associations between chronoactivity and multiple CVD outcomes…